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Here is the Week 10 schedule across North Carolina with Guru’s Gameday Picks.
| Guru’s Pick | |
| A.C. Reynolds (5-3) at T.C. Roberson (2-6) | A.C. Reynolds |
| A.L. Brown (4-4) at Mooresville (4-4) | Mooresville |
| Alexander Central (4-4) at Hibriten (4-3) | Alexander Central |
| Andrews (5-2) at Robbinsville (3-3) | Robbinsville |
| Asheville (6-2) at North Buncombe (0-6) | Asheville |
| Aycock (1-7) at Smithfield-Selma (5-3) | Smithfield-Selma |
| Bandys (2-4) at West Caldwell (0-7) | Bandys |
| Bartlett Yancey (5-3) at Jordan-Matthews (0-8) | Bartlett Yancey |
| Ben L. Smith (3-5) at Eastern Guilford (6-1) | Eastern Guilford |
| Broughton (0-8) at Enloe (1-7) | Enloe |
| Bunker Hill (7-1) at Newton-Conover (3-4) | Newton-Conover |
| Burns (6-2) at Cherryville (2-6) | Burns |
| Camden County (3-5) at Holmes (5-2) | Holmes |
| Cardinal Gibbons (6-2) at Athens Drive (1-6) | Cardinal Gibbons |
| Carson (2-5) at Central Cabarrus (2-5) | Carson |
| Central Davidson (7-0) at North Davidson (4-3) | North Davidson |
| Charlotte Christian (3-4) at Christ School (2-4) | Charlotte Christian |
| Charlotte Country Day (1-6) at Charlotte Latin (7-1) | Charlotte Latin |
| Cherokee (4-3) at Hayesville (2-6) | Cherokee |
| Christ the King (2-6) at Community School of Davidson (6-2) | CSOD |
| Clinton (5-2) at West Bladen (3-4) | Clinton |
| Cox Mill (4-4) at Hickory Ridge (6-2) | Hickory Ridge |
| Cuthbertson (3-5) at Weddington (7-1) | Weddington |
| Dixon (1-5) at Croatan (3-5) | Croatan |
| East Carteret (3-4) at Southside (6-1) | Southside |
| East Chapel Hill (0-7) at Cummings (6-1) | Cummings |
| East Davidson (4-4) at Thomasville (6-1) | Thomasville |
| East Duplin (7-1) at Wallace-Rose Hill (7-1) | Wallace-Rose Hill |
| East Henderson (1-6) at Pisgah (7-1) | Pisgah |
| East Mecklenburg (1-7) at Charlotte Catholic (6-2) | Charlotte Catholic |
| East Wake (3-5) at South Johnston (6-2) | South Johnston |
| Elkin (3-4) at Mt. Airy (8-0) | Mt. Airy |
| Erwin (4-4) at McDowell (5-2) | McDowell |
| Fike (5-2) at Southern Wayne (1-6) | Fike |
| First Flight (2-5) at Pasquotank County (0-6) | First Flight |
| Forbush (5-3) at North Wilkes (2-5) | Forbush |
| Franklin (5-3) at West Henderson (2-6) | Franklin |
| Fred T. Foard (0-7) at Hickory (5-3) | Hickory |
| Fuquay-Varina (6-3) at South Garner (4-4) | Fuquay-Varina |
| Garner (3-3) at Cleveland (7-0) | Cleveland |
| Gates County (2-3) at Perquimans (4-2) | Perquimans |
| Glenn (6-1) at East Forsyth (6-1) | East Forsyth |
| Goldsboro (3-5) at Spring Creek (3-4) | Goldsboro |
| Graham (4-3) at North Moore (7-1) | North Moore |
| Granville Central (0-8) at Carrboro (1-7) | Granville Central |
| Green Level (1-7) at Green Hope (3-4) | Green Hope |
| Greene Central (3-6) at Farmville Central (2-6) | Greene Central |
| Havelock (5-2) at Northside-Jax (0-8) | Havelock |
| Hendersonville (6-1) at Brevard (3-4) | Hendersonville |
| Hertford County (6-2) at Manteo (1-7) | Hertford County |
| High Point Central (3-5) at Atkins (1-6) | High Point Central |
| Highland Tech (1-7) at Thomas Jefferson (4-3) | Thomas Jefferson |
| Hoggard (7-1) at Laney (7-1) | Hoggard |
| Hoke County (4-5) at Pinecrest (6-2) | Pinecrest |
| Holly Springs (5-3) at Apex (4-4) | Apex |
| Hunt (7-1) at West Johnston (4-3) | Hunt |
| Hunter Huss (0-6) at Crest (5-2) | Crest |
| J.F. Webb (3-3) at South Granville (2-6) | South Granville |
| J.M. Robinson (7-1) at South Stanly (1-6) | Robinson |
| Jack Britt (3-4) at Gray’s Creek (4-4) | Jack Britt |
| James Kenan (4-2) at Southwest Onslow (2-5) | Southwest Onslow |
| John Paul II (7-1) at Hobbton (2-6) | Hobbton |
| Jones Senior (2-5) at Pamlico County (2-5) | Pamlico County |
| Jordan (3-3) at Southern Alamance (7-1) | Southern Alamance |
| Kings Mountain (7-1) at Ashbrook (1-5) | Kings Mountain |
| KIPP Pride (3-3) at Weldon (3-2) | Weldon |
| Lake Norman (6-2) at South Iredell (2-6) | Lake Norman |
| Ledford (6-2) at Asheboro (1-7) | Ledford |
| Leesville Road (6-1) at Sanderson (4-2) | Leesville Road |
| Lejeune (0-8) at Northside (7-1) | Northside Pinetown |
| Louisburg (4-2) at Nash Central (4-4) | Nash Central |
| Lumberton (1-6) at Seventy-First (8-0) | Seventy-First |
| Maiden (8-0) at Lincolnton (4-4) | Maiden |
| Marvin Ridge (6-1) at Sun Valley (2-6) | Marvin Ridge |
| McMichael (6-2) at Reidsville (7-0) | Reidsville |
| Metrolina Christian (7-1) at Cabarrus Warriors (6-1) | Cabarrus |
| Middle Creek (6-2) at Apex Friendship (3-5) | Middle Creek |
| Midway (5-3) at East Bladen (3-5) | Midway |
| Millbrook (7-1) at Knightdale (3-4) | Millbrook |
| Mitchell (6-2) at Rosman (0-7) | Mitchell |
| Monroe (4-1) at West Stanly (2-4) | Monroe |
| Montgomery Central (0-7) at Oak Grove (5-2) | Oak Grove |
| Mount Tabor (3-4) at Reagan (5-3) | Reagan |
| Mountain Heritage (5-2) at Madison (4-4) | Mountain Heritage |
| Mountain Island Charter (7-1) at Carver (4-4) | MICS |
| Murphy (5-3) at Swain County (4-2) | Murphy |
| New Bern (8-1) at D.H. Conley (3-5) | New Bern |
| North Brunswick (4-3) at South Brunswick (6-2) | South Brunswick |
| North Duplin (3-4) at Rosewood (3-2) | Rosewood |
| North Edgecombe (3-5) at Rocky Mount Prep (0-4) | North Edgecombe |
| North Henderson (4-4) at Enka (3-5) | North Henderson |
| North Iredell (2-5) at East Lincoln (6-2) | East Lincoln |
| North Johnston (2-6) at Eastern Wayne (6-2) | Eastern Wayne |
| North Lenoir (3-4) at South Lenoir (2-5) | North Lenoir |
| North Mecklenburg (4-3) at Hopewell (1-7) | North Mecklenburg |
| North Pitt (6-2) at West Craven (3-3) | North Pitt |
| North Stanly (3-4) at Mount Pleasant (6-2) | Mount Pleasant |
| North Stokes (4-5) at South Stokes (3-4) | South Stokes |
| Northampton (6-2) at Warren County (2-4) | Northampton |
| Northeastern (7-0) at Currituck County (4-4) | Northeastern |
| Northern Nash (7-1) at Southern Nash (7-0) | Northern Nash |
| Northwood (4-3) at Eastern Alamance (5-1) | Eastern Alamance |
| Olympic (5-2) at Ardrey Kell (5-2) | Ardrey Kell |
| Orange (2-6) at Williams (4-4) | Williams |
| Owen (2-6) at Avery County (1-7) | Owen |
| Page (4-4) at Grimsley (8-0) | Grimsley |
| Panther Creek (6-2) at Cary (3-5) | Panther Creek |
| Parkland (1-7) at Davie County (5-3) | Davie County |
| Parkwood (4-2) at Anson County (3-5) | Parkwood |
| Patton (2-5) at Chase (7-1) | Chase |
| Pine Forest (7-1) at Harnett Central (2-5) | Pine Forest |
| Pine Lake Prep (5-2) at Lake Norman Charter (5-2) | Pine Lake Prep |
| Polk County (4-3) at Draughn (5-3) | Polk County |
| Porter Ridge (4-2) at Piedmont (2-6) | Porter Ridge |
| Providence (4-4) at Garinger (1-6) | Providence |
| Purnell Swett (0-4) at Douglas Byrd (0-8) | Purnell Swett |
| Rabun Gap-Nacoochee (6-1) at Providence Day (4-3) | Rabun Gap |
| Randleman (3-5) at Trinity (4-4) | Randleman |
| Ravenscroft (6-2) at Harrells Christian (7-1) | Harrells |
| Richlands (0-6) at White Oak (6-2) | White Oak |
| Riverside (2-6) at Chapel Hill (5-3) | Chapel Hill |
| Roanoke Rapids (5-3) at Bunn (2-6) | Roanoke Rapids |
| Rockingham County (3-4) at Northeast Guilford (1-7) | Rockingham |
| Rocky Mount (5-3) at Franklinton (2-5) | Rocky Mount |
| Rocky River (2-6) at Independence (3-4) | Independence |
| Scotland (5-2) at Lee County (5-3) | Scotland |
| Shelby (7-1) at East Gaston (5-3) | Shelby |
| South Caldwell (6-1) at Ashe County (1-6) | South Caldwell |
| South Central (1-5) at Jacksonville (5-2) | Jacksonville |
| South Columbus (3-3) at East Columbus (3-4) | South Columbus |
| South Creek (0-7) at Riverside Martin (3-2) | Riverside Martin |
| South Davidson (1-6) at West Davidson (1-6) | West Davidson |
| South Mecklenburg (6-2) at Myers Park (6-2) | Myers Park |
| South Point (5-3) at Forestview (4-4) | South Point |
| South Rowan (1-7) at East Rowan (0-7) | South Rowan |
| South View (6-2) at Cape Fear (5-2) | South View |
| Southeast Guilford (5-3) at Northwest Guilford (4-4) | Southeast Guilford |
| Southeast Halifax (2-6) at Northwest Halifax (1-4) | Southeast Halifax |
| Southeast Raleigh (2-5) at Corinth Holders (3-4) | Corinth Holders |
| Southern Durham (4-4) at Vance County (6-1) | Southern Durham |
| Southern Guilford (3-5) at Dudley (7-1) | Dudley |
| Southern Lee (0-7) at Union Pines (1-7) | Union Pines |
| Southlake Christian (0-6) at High Point Christian (3-4) | High Point Christian |
| SouthWest Edgecombe (3-4) at Washington (6-2) | Washington |
| Southwest Guilford (3-5) at Ragsdale (1-7) | Southwest Guilford |
| Southwestern Randolph (7-1) at Providence Grove (6-2) | SW Randolph |
| St. Pauls (6-0) at Fairmont (2-5) | St. Pauls |
| Starmount (4-4) at Alleghany (2-5) | Starmount |
| Statesville (7-0) at St. Stephens (1-6) | Statesville |
| Stuart Cramer (4-4) at North Gaston (1-7) | Stuart Cramer |
| Surry Central (6-2) at North Surry (3-4) | North Surry |
| Swansboro (4-3) at West Carteret (5-2) | West Carteret |
| Terry Sanford (4-3) at E.E. Smith (0-7) | Terry Sanford |
| Topsail (2-5) at Ashley (1-6) | Topsail |
| Trask (0-7) at Whiteville (7-0) | Whiteville |
| Trinity Christian (2-4) at Forest Hills (5-3) | Forest Hills |
| Triton (1-6) at Overhills (3-4) | Overhills |
| Tuscola (5-3) at Smoky Mountain (5-2) | Tuscola |
| Union Academy (0-8) at Albemarle (1-6) | Albemarle |
| Wake Forest (6-2) at Rolesville (5-3) | Rolesville |
| Wakefield (4-4) at Heritage (7-1) | Heritage |
| Walkertown (4-4) at Morehead (2-6) | Walkertown |
| Washington County (2-3) at Bertie (1-5) | Washington County |
| Watauga (6-2) at Freedom (4-3) | Watauga |
| West Brunswick (2-5) at New Hanover (4-4) | West Brunswick |
| West Cabarrus (3-5) at Hough (8-0) | Hough |
| West Charlotte (5-2) at Chambers (7-1) | Chambers |
| West Columbus (3-4) at Pender (4-3) | Pender |
| West Forsyth (5-3) at R.J. Reynolds (2-6) | West Forsyth |
| West Iredell (1-5) at North Lincoln (6-2) | North Lincoln |
| West Lincoln (6-2) at East Burke (1-5) | West Lincoln |
| West Mecklenburg (4-5) at Mallard Creek (3-3) | Mallard Creek |
| West Rowan (5-2) at Concord (5-2) | West Rowan |
| West Stokes (4-3) at North Forsyth (3-5) | North Forsyth |
| Western Guilford (1-6) at Northern Guilford (8-0) | Northern Guilford |
| Western Harnett (2-5) at Westover (6-1) | Westover |
| Wheatmore (3-4) at Eastern Randolph (7-0) | Eastern Randolph |
| Winston-Salem Prep (0-7) at Bishop McGuinness (1-6) | W-S Prep |
